Publications

Trang Dinh, Mira Rahm, Zhenghe Wang, Christopher McFarland, Athar Khalil (2024). Exploring the molecular landscape of NNK-induced transformation: A comprehensive genome-wide CRISPR/Cas9 screening. Genes & Diseases.

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Yuxiang Wang, Athar Khalil, Amina Kamar, Mengyan Du, Trang Dinh, Christopher Mcfarland, Zhenghe Wang (2023). Unveiling immune checkpoint regulation : exploring the power of in vivo CRISPR screenings in cancer immunotherapy. Frontiers in Genetics.

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Jian Tian, Christopher D. McFarland, Jaie Woodard (2023). Editorial: Structural understanding of the functional consequences of missense mutation. Frontiers in Genetics.

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Chuan Li, Wen-Yang Lin, Hira Rizvi, Hongchen Cai, Christopher D McFarland, Zoe N Rogers, Maryam Yousefi, Ian P Winters, Charles M Rudin, Dmitri A Petrov, Monte M Winslow (2021). Quantitative in vivo analyses reveal a complex pharmacogenomic landscape in lung adenocarcinoma.. Cancer research.

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Hongchen Cai, Su Kit Chew, Chuan Li, Min K Tsai, Laura Andrejka, Christopher W. Murray, Nicholas W. Hughes, Emily G. Shuldiner, Emily L. Ashkin, Rui Tang, King L. Hung, Leo C. Chen, Shi Ya C. Lee, Maryam Yousefi, Wen-Yang Lin, Christian A. Kunder, Le Cong, Christopher D. McFarland, Dmitri A Petrov, Charles Swanton, Monte M. Winslow (2021). A functional taxonomy of tumor suppression in oncogenic KRAS-driven lung cancer. Cancer Discovery.

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Zoë N. Rogers, Christopher D. McFarland, Ian P. Winters, Jose A. Seoane, Jennifer J. Brady, Stephanie Yoon, Christina Curtis, Dmitri A. Petrov, Monte M. Winslow (2018). Mapping the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice. Nature Genetics.

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MM Winslow, Petrov DA, I Winters, Christopher D. McFarland, ZN Rogers (2018). Compositions and methods for multiplexed quantitative analysis of cell lineages.

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Ian P Winters, Shin-Heng Chiou, Nicole K Paulk, Christopher D McFarland, Pranav V Lalgudi, Rosanna K Ma, Leszek Lisowski, Andrew J Connolly, Dmitri A Petrov, Mark A Kay, Monte M Winslow (2017). Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity. Nature Communications.

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Christopher D McFarland, Julia A Yaglom, Jonathan W Wojtkowiak, Jacob G Scott, David L Morse, Michael Y Sherman, Leonid A Mirny (2017). The Damaging Effect of Passenger Mutations on Cancer Progression.. Cancer research.

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Zoë N Rogers, Christopher D McFarland, Ian P Winters, Santiago Naranjo, Chen-Hua Chuang, Dmitri Petrov, Monte M Winslow (2017). A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo. Nature Methods.

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Christopher D. McFarland (2016). A modified ziggurat algorithm for generating exponentially and normally distributed pseudorandom numbers. Journal of Statistical Computation and Simulation.

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Christopher D McFarland, Leonid a Mirny, Kirill S Korolev (2014). Tug-of-war between driver and passenger mutations in cancer and other adaptive processes. Proceedings of the National Academy of Sciences.

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Julia A Yaglom, Christopher McFarland, Leonid Mirny, Michael Y Sherman (2014). Oncogene-triggered suppression of DNA repair leads to DNA instability in cancer.. Oncotarget.

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Christopher D McFarland, Kirill S Korolev, Gregory V Kryukov, Shamil R Sunyaev, Leonid a Mirny (2013). Impact of deleterious passenger mutations on cancer progression. Proceedings of the National Academy of Sciences.

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