Publications

(2020). Quantitative in vivo analyses reveal a complex pharmacogenomic landscape in lung adenocarcinoma.

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(2019). Most cancers carry a substantial deleterious load due to Hill-Robertson interference.

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(2018). Mapping the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice. Nature Genetics.

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(2018). Compositions and methods for multiplexed quantitative analysis of cell lineages.

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(2017). Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity. Nature Communications.

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(2017). The Damaging Effect of Passenger Mutations on Cancer Progression.. Cancer research.

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(2017). A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo. Nature Methods.

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(2016). A modified ziggurat algorithm for generating exponentially and normally distributed pseudorandom numbers. Journal of Statistical Computation and Simulation.

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(2014). Tug-of-war between driver and passenger mutations in cancer and other adaptive processes. Proceedings of the National Academy of Sciences.

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(2014). Oncogene-triggered suppression of DNA repair leads to DNA instability in cancer.. Oncotarget.

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(2013). Impact of deleterious passenger mutations on cancer progression. Proceedings of the National Academy of Sciences.

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